PhD candidates

Annemarie Berends, PhD candidate

annemarie.berends@radboudumc.nl

Affiliation:Radboudumc, Nijmegen
Supervision:Peter Friedl
Project title:
Cancer metastasis and immunotherapy – monitoring drug effects in vivo
Keywords:
anti-tumour immune response, cytoskeleton, intravital microscopy, drugs in action

Work package involvement:

BioWP2.3 Immunological cell clearance in regeneration and cancer
BioWP3.2 Interrogation and validation of drug mechanisms


ECR committee Rep
Enya Berrevoets, PhD candidate

e.s.berrevoets@tudelft.nl

Affiliation:Delft University of Technology, Delft
Supervision:Sjoerd Stallinga
Project title:
Developing computational methods for high-resolution 3D
microscopy

Keywords:computational imaging, image reconstruction, data analysis

Work package involvement:

TechWP1.1 Subcellular live-imaging in transparent tissue
TechWP2.2 Automated control of microscopy



Sabine Bosman, PhD candidate

s.l.bosman-8@umcutrecht.nl

Affiliation:University Medical Center Utrecht, Utrecht
Supervision:Madelon Maurice
Project title:

Intra-epithelial responses to tissue damage in intestinal organoids

Keywords:tissue repair, cell polarity, cell-cell communication, optogenetics

Work package involvement:

BioWP1.1 Cell proliferation and renewal: self-organisation at the tissue level
BioWP1.2 Cell differentiation: subcellular self-organisation and emergence of specialized cell functions
BioWP2.1 Normal tissue repair: de-differentiation, cell division, cell migration
BioWP2.2 Tissue self-organisation gone awry: cancer initiation and progression
TechWP2.3 Innovative actuation strategies 


ECR committee Vice Rep
Alessandro Corsini, PhD candidate

a.corsini@hubrecht.eu

Affiliation:Hubrecht Institute, Utrecht
Supervision:Geert Kops
Project title:
The roles of mitotic spindle orientation in intestinal homeostasis and tumorigenesis.
Keywords:organoids micropatterning, tumorigenesis, spindle orientation

Work package involvement:

BioWP1.1 Cell proliferation and renewal: self-organisation at the tissue level
BioWP2.1 Normal tissue repair: de-differentiation, cell division, cell migration
BioWP2.2 Tissue self-organisation gone awry: cancer initiation and progression



Ralph de Groot, PhD candidate

r.a.degroot@uu.nl

Affiliation:Utrecht University, Utrecht
Supervision:Roos Masereeuw, Silvia Mihăilă, Manoe Janssen
Project title:

Drug resistance in advanced in vitro cultures of epithelial tissues

Keywords:microfluidics, organ-on-a-chip, cell differentiation

Work package involvement:

BioWP1.3 Cell migration: self-organisation during tissue rearrangement
BioWP2.1 Normal tissue repair: de-differentiation, cell division, cell migration
BioWP3.1 Drug effects on tissues at the cellular and subcellular level
BioWP3.2 Interrogation and validation of drug mechanisms
TechWP1.5 Label-free sensing strategies for drugs and biomarkers


Vincent Hellebrekers, PhD candidate

v.j.w.hellebrekers@uu.nl

Affiliation:Utrecht University, Utrecht
Supervision:Ihor Smal, Lukas Kapitein
Project title:

Real-Time Image Analysis for Smart Microscopy

Keywords:AI, programming, image analysis, smart microscopy

Work package involvement:

TechWP2.1 Real-time data analysis
TechWP2.2 Automated control of microscopy
TechWP2.4 Automated control of biology 



Nefeli Ithakisiou, PhD candidate

g.n.ithakisiou-2@umcutrecht.nl

Affiliation:University Medical Center Utrecht, Utrecht
Supervision:Jeffrey Beekman, Bahar Arik
Project title:
High resolution imaging of patient-derived airway cells for diagnosis and treatment of primary ciliary dyskinesia
Keywords:airway cells, cell and tissue repair

Work package involvement:

BioWP1.1 Cell proliferation and renewal: self-organisation at the tissue level
BioWP1.2 Cell differentiation: subcellular self-organisation and emergence of specialized cell functions
BioWP2.1 Normal tissue repair: de-differentiation, cell division, cell migration 



Angelique Kenyon, PhD candidate

angelique.kenyon@radboudumc.nl

Affiliation:Radboudumc, Nijmegen
Supervision:Annemiek van Spriel
Project title:

Membrane organisation in lymphocytes and therapeutic targets

Keywords:immune cells, drugs in action, membrane organisation

Work package involvement:

BioWP1.2 Cell differentiation: subcellular self-organisation and emergence of specialized cell functions
BioWP2.3 Immunological cell clearance in regeneration and cancer
BioWP3.1 Drug effects on tissues at the cellular and subcellular level
BioWP3.2 Interrogation and validation of drug mechanisms 


ECR committee
Danai Kokkinidi, PhD candidate

D.Kokkinidi-2@umcutrecht.nl

Affiliation:University Medical Center Utrecht, Utrecht
Supervision:Madelon Maurice, Geert Kops
Project title:
Deciphering the role of apicobasal polarity during intestinal epithelial development, homeostasis and cancer
Keywords:organoids, apicobasal polarity, tissue organization, cancer biology

Work package involvement:

BioWP1.1 Cell proliferation and renewal: self-organisation at the tissue level
BioWP1.2 Cell differentiation: subcellular self-organisation and emergence of specialized cell functions
BioWP2.1 Normal tissue repair: de-differentiation, cell division, cell migration
BioWP2.2 Tissue self-organisation gone awry: cancer initiation and progression



Menno van Laarhoven, PhD candidate

m.t.p.vanlaarhoven@tudelft.nl

Affiliation:Delft University of Technology, Delft
Supervision:Carlas Smith, Sjoerd Stallinga
Project title:
Control of cellular processes through smart microscopy
Keywords:computational imaging, smart microscopy, super resolution, quantitative imaging, image analysis

Work package involvement:

TechWP1.1 Subcellular live-imaging in transparent tissue
TechWP1.2 Deeper live-imaging in mice
TechWP2.2 Automated control of microscopy
TechWP2.4 Automated control of biology 


ECR committee
Tatum van Maanen, PhD candidate

t.v.maanen@nki.nl

Affiliation:Netherlands Cancer Institute, Amsterdam
Supervision:Jacco van Rheenen, Hugo Snippert
Project title:

Taxane activation of T-cells for improved T-cell therapy

Keywords:immune cells, drugs in action

Work package involvement:

BioWP1.1 Cell proliferation and renewal: self-organisation at the tissue level
BioWP1.3 Cell migration: self-organisation during tissue rearrangement
BioWP2.1 Normal tissue repair: de-differentiation, cell division, cell migration
BioWP2.2 Tissue self-organisation gone awry: cancer initiation and progression
BioWP3.1 Drug effects on tissues at the cellular and subcellular level
BioWP3.2 Interrogation and validation of drug mechanisms
TechWP1.2 Deeper live-imaging in mice
TechWP1.3 Quantitative imaging with sensors across systems
TechWP1.5 Label-free sensing strategies for drugs and biomarkers 



Maud Linssen, PhD candidate

m.d.m.e.linssen@tue.nl

Affiliation:Eindhoven University of Technology, Eindhoven
Supervision:Menno Prins, Arthur de Jong
Project title:

Continuous biomolecular monitoring

Keywords:biosensors, microdialysis, biosensing by particle motion

Work package involvement:

BioWP3.1 Drug effects on tissues at the cellular and subcellular level 
TechWP1.5  Label-free sensing strategies for drugs and biomarkers


ECR Committee
Thijs Makaske, PhD candidate

t.b.makaske@uu.nl

Affiliation:Utrecht University, Utrecht
Supervision:Lukas Kapitein
Project title:

Microvillus inclusion disease and optogenetics

Keywords:optogenetics, intestinal organoids, microvillus inclusion disease

Work package involvement:

BioWP1.2 Cell differentiation: subcellular self-organisation and emergence of specialized cell functions
BioWP1.3 Cell migration: self-organisation during tissue rearrangement
TechWP1.1 Subcellular live-imaging in transparent tissue
TechWP1.4 Innovative labelling strategies for Expansion Microscopy
TechWP2.1 Real-time data analysis
TechWP2.2 Automated control of microscopy
TechWP2.3 Innovative actuation strategies
TechWP2.4 Automated control of biology



Frederique Turlings, PhD candidate

frederique.turlings@radboudumc.nl

Affiliation:Radboudumc, Nijmegen
Supervision:Martijn Verdoes
Project title:
Design and synthesis of a molecular toolbox for expansion microscopy
Keywords:organic chemistry, labelling strategies, expansion microscopy

Work package involvement:

BioWP2.2 Tissue self-organisation gone awry: cancer initiation and progression
BioWP2.3 Immunological cell clearance in regeneration and cancer
TechWP1.4 Innovative labelling strategies for Expansion Microscopy
TechWP2.3 Innovative actuation strategies